A Brief Description Of Aldosterone

The bodys adrenal gland is responsible for the secernment of the steroid internal secretion aldosterone. The latters main function is to get and balance piddle and salt in the human system (otherwise know as the electrolyte metabolism of the body). As an extremely potent hormone, aldosterone promotes atomic number 11 keeping and enhances potassium excretion in the system. The hormone withal helps regulate strain pressure and bodily fluids hence if the aldosterone levels ar low or withal blue, symptoms can result.Aldosterone directly acts on the kidneys tubules and controls their reabsorption of more sodium and water from the urine. Secretion of potassium in the tubule replaces the sodium, which is then reabsorbed. Another function of the hormone is to operate on a persons central restless system to influence the increase of a persons proclivity for salt and their thirst. Aldosterone secretion is the result of two different bodily mechanisms. It is hypothesized that if so dium concentrates in the system are severely limited, it may author change magnitude rates of aldosterone.Another theory is that reduced crinkle flow to the kidney engages it to release the enzyme chymosin which then converts inactive globulin in the gunstock. Other than these, studies showed that the hormone may present other target cells than originally remarked on. The editors of the Kidney International Journal in 2000 (Farman and Verrey) commented on Dr. Haim Gartys observation that there is Aldosterone action in non-epithelial cells. Hence it is seen that asunder from the kidneys, the hormone is also linked to the central nervous and cardiovascular systems as well as various membrane lipids.Amplified levels of aldosterone secretion often cause salt retention which in turn results in edema. Extremely high levels of the hormone can result to high blood pressure, muscle cramps and over-all fatigue. On the other hand, low levels may be an indicator of diabetes. It is prove n that the fun of the hormone levels are influenced by the persons sex as well as the amount of sodium consumed in his or her periodical diet. Pregnancy may lead to higher(prenominal) levels of aldosterone in women. Other symptoms of higher than normal levels of aldosterone may also result to primary or junior-grade hyperaldosteronism.Primary hyperaldosteronism is considered as a rare syndrome caused by an abnormality in the adrenal gland. More often than not, the gland is affected by a benign tumor and this often transpires between t hags of 30 and 50 years old. Secondary hyperaldosteronism is generally related to high blood pressure and other disorders such as cardiac failure, cirrhosis of the coloured and nephritic syndrome. Various mechanisms affect the disease and causes the imbalance of the hormones levels in the human system.Another extremely rare disease linked to aldosterone is the Barrter syndrome which also affects the kidneys. Patients diagnosed with the Barrter Synd rome experiences loss of potassium and an increase in aldosterone. This results to potassium wasting where the kidneys take away far too much necessary potassium from the body. Incidentally, there are tests to check the aldosterone levels in the body. It is often don concurrently with other blood tests or provocative tests to determine over or under merchandise of the hormone.